Homocellular Conduction Along Endothelium and Smooth Muscle of Arterioles in Hamster Cheek Pouch
نویسندگان
چکیده
منابع مشابه
Homocellular conduction along endothelium and smooth muscle of arterioles in hamster cheek pouch: unmasking an NO wave.
We investigated roles for homocellular (endothelium or smooth muscle) and heterocellular (myoendothelial) conduction pathways along hamster cheek pouch arterioles in vivo (n=64; diameter, 33+/-1 microm). Endothelium-dependent and -independent vasoactive agents were delivered from micropipettes (0.5 or 1 second pulse) onto an arteriole while observing diameter changes at defined distances along ...
متن کاملResolution of smooth muscle and endothelial pathways for conduction along hamster cheek pouch arterioles.
In the cheek pouch of anesthetized male hamsters, microiontophoresis of Ach (endothelium-dependent vasodilator) or phenylephrine (PE; smooth muscle-specific vasoconstrictor) onto an arteriole (resting diameter, 30-40 microm) evokes vasodilation or vasoconstriction (amplitude, 15-25 microm), respectively, that conducts along the arteriolar wall. In previous studies of conduction, endothelial and...
متن کاملRole of EDHF in conduction of vasodilation along hamster cheek pouch arterioles in vivo.
We tested whether local and conducted responses to ACh depend on factors released from endothelial cells (EC) in cheek pouch arterioles of anesthetized hamsters. ACh was delivered from a micropipette (1 s, 500 nA), while arteriolar diameter (rest, approximately 40 microm) was monitored at the site of application (local) and at 520 and 1,040 microm upstream (conducted). Under control conditions,...
متن کاملCapillaries and arterioles are electrically coupled in hamster cheek pouch.
In this report we demonstrate electrical communication in the microcirculation between arterioles and capillary networks in situ. Microvessel networks in the hamster cheek pouch, which included capillaries and their feeding arterioles, were labeled with the voltage-sensitive dye di-8-ANEPPS by intraluminal perfusion through a micropipette. Pulses of 140 mM potassium solution were applied by pre...
متن کاملBobbing along on the crest of a wave: NO ascends hamster cheek pouch arterioles.
The resistance network that controls blood flow to skeletal muscle comprises terminal arterioles, as well as larger arterioles and the small (feeder) arteries from which they derive. For example, in a contracting skeletal muscle, low PO2 and vasoactive metabolites elicit a local response and initiate a conducted vasodilatation that “ascends” the vascular tree to induce the simultaneous vasodila...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2003
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.0000080318.81205.fd